Nina Meurisse went to the Conservatory and studied music, piano, singing, harp, dance and the dramatic arts. She was first seen on the silver screen at the age of 12 opposite Isabelle Huppert in "Saint-Cyr" by Patricia Mazuy, presented in the Official Selection at Cannes 2000. Two years later, she appeared in "Des épaules solides" by Ursula Meier. She made a short film in 2002, "Petit traité de marketing", that won the Prix de l'Humour at the Houlgate Festival and then appeared in several shorts by Frederic Mermoud: "L'Escalier" in 2003 and "Rachel" in 2006, and then her first lead role in his first feature "Accomplices" en 2010.