Frank Martin, an ex-mercenary from the special forces, is now a specialist in transporting top secret packets for clients who are not always very commendable. While his father comes to visit him in the south of France, Frank finds himself dragged into a hold-up by Anna, a mysterious and manipulative client, and her three partners. Thrown into the middle of a ruthless vendetta carried out by these four femmes fatales, while the shadow of the Russian mafia hovers over the Riviera, Frank must call on his driving and ladykiller skills more than ever.