In a murderous fit of jealousy, the renowned Collège de France professor, Henri Toussaint, tried to slit his wife's throat after he caught her in bed with a barman. For seven years, he has been incarcerated in a private psychiatric clinic. One day, his psychiatrist, Bertrand Daumale, asks him to meet with his wife for a week-end. She is terminally ill and wants to offer him her forgiveness before leaving this world. After all, it's nothing more than a two-hour car trip at the end of which the professor will receive a farewell kiss which allow him to reconstruct his life - a life that was blown apart in a momentary fit of madness. But... at the last minute, another of the clinic's insanes, a psychotic named Angel, hides himself away in the psychiatrist's car. Angel, a sort of Harpo Marx figure, has the annoying habit of standing on people's feet and pulling the hairs in their nose, all the while giving them a broad smile. So here is the infortunate Bertrand Daumale landed with two companions who quickly prove themselves to be completely unmanageable...
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