Through a series of circumstances and plot twists too numerous to mention, Paul Braconnier, an enterprising man (Michel Simon), manages to get away with murdering his wife Blandine, even though he cheerfully admits his guilt in court. The murderer's defense strategy is targeted towards every man who has ever wished that his wife would simply disappear.
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La Poison was loosely remade in 1966 as the Jack Lemmon comedy How to Murder Your Wife.